Coke - heart and liver problems mostly but it tends to require long term use so as long as you don't develop a habit you're pretty safe stuffing a line or 3 up your nose once in a while. That does assume you're getting decent, clean coke - which isn't likely if you're only buying it a gram at a time. Pills are a tricky one, MDMA in itself isn't that bad for you - obviously you'll get the heart and liver problems associated with any stimulant and you'll almost certainly suffer depression if you take it in the volumes me and my mates did (ie. almost every day). The problem with pills is that you're not just getting mdma - you'll find you're eating ketamine, cocaine, smack, speed and all sorts of other stuff as well as the mdma (if there's any mdma in it at all). er yeah, drugs are bad. don't do drugs